Naive Application of Permutation Testing Leads to Inflated Type I Error Rates
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چکیده
منابع مشابه
Naive application of permutation testing leads to inflated type I error rates.
Failure to account for family structure within populations or in complex mating designs via uninformed applications of permutation testing will lead to inflated type I error rates. Careful consideration of the design factors is essential since some situations allow several valid permutation strategies, and the choice that maximizes statistical power will not always be intuitive.
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The present article proposes general single-step multiple testing procedures for controlling Type I error rates defined as arbitrary parameters of the distribution of the number of Type I errors, such as the generalized family-wise error rate. A key feature of our approach is the test statistics null distribution (rather than data generating null distribution) used to derive cut-offs (i.e., rej...
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Type I Error Rates and Power of Multiple Hypothesis Testing Procedures in Factorial ANOVA
There are numerous General Linear Model (GLM) statistical designs that may require multiple hypothesis testing (MHT) procedures that control the Type I error inflation that occurs with multiple tests. This study investigated familywise error rates (FWER) and statistical power rates of several alpha-adjustment MHT procedures in factorial ANOVA, but results apply broadly to GLM procedures. Of fou...
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ژورنال
عنوان ژورنال: Genetics
سال: 2008
ISSN: 1943-2631
DOI: 10.1534/genetics.107.074609